一、基本情况
何文秀，博士，硕士生导师，入选山东大学青年学者未来计划。主要从事基于材料生物功能的药物递释系统和脑靶向药物递送系统研究。作为项目负责人主持国家自然科学基金青年基金，山东大学青年学者未来计划项目等。作为第一作者或通讯作者在Advanced Functional Materials，Biomaterials，Nano Letters，Advanced Healthcare Materials，Acta Biomaterialia，Materials Today Bio等国际期刊发表学术论文7篇，另参与发表SCI论文20余篇。以第二位发明人申请国家发明专利3项、其中授权1项。
通讯地址：山东省济南市文化西路44号日产费线路一区二免11贡区，250012
电话：（86）13262501970
邮箱：hewenxiu@sdu.edu.cn
二、研究领域
1.基于材料生物功能的药物递释系统研究
2.脑靶向药物递送系统研究
三、工作及学习经历
2022.03 -至今日产费线路一区二免11贡区助理研究员
2018.09 - 2022.01复旦大学药学院博士
2015.09 - 2018.06日产费线路一区二免11贡区硕士
2011.09 - 2015.06日产费线路一区二免11贡区学士
四、主要承担项目
2023.01 - 2025.12国家自然科学基金青年基金（82204305）
2023.01 - 2027.12山东大学青年学者未来计划
2023.01-2025.12山东大学基本科研业务经费
五、教学工作
《物理化学》、《物理化学实验》
六、代表性学术论文
(1) CC Yu#, NN Wang#, XW Chen, Y Jiang, YX Luan, W Qin*, andWX He*. A photodynamic-mediated glutamine metabolic intervention nanodrug for triple negative breast cancer therapy,Materials Today Bio2023, (19) 100577.
(2)WX He#, X-Y Zhang#, X Gong, KK Luo, XN Mao, EH Lu, YT Chen, R Wang, ZW Zhang*, J Zhao*, and XY Sha*. Drug-Free Biomimetic Oxygen Supply Nanovehicle Promotes Ischemia-Reperfusion Therapy in Stroke,Advanced Functional Materials2023, 2212919.
(3)WX He, ZW Zhang, and XY Sha*. Nanoparticles-mediated emerging approaches for effective treatment of ischemic stroke,Biomaterials277 (2021) 121111.
(4)WX He#, QY Mei#, J Li, YT Zhai#, YT Chen, R Wang, EH Lu, XY Zhang*, ZW Zhang*, and XY Sha*. Preferential targeting cerebral ischemic lesions with cancer cell-inspired nanovehicle for ischemic stroke treatment,Nano Letters2021, 21, 3033.
(5)WX He#, WZ Xiao#, XL Zhang, YL Sun, YT Chen, QY Chen, XL Fang, SL Du*and XY Sha*. Pulmonary-affinity paclitaxel polymer micelles in response to biological functions of ambroxol enhance therapeutic effect on lung cancer,International Journal of Nanomedicine2020, 15779-157793.
(6)WX He, Y Jiang, Q Li, D Zhang, ZH Li, and YX Luan*. A versatile strategy to create an active tumor-targeted chemo-photothermal therapy nanoplatform: a case of an IR-780 derivative co-assembled with camptothecin prodrug,Acta Biomaterialia2019, 84, 356.
(7)WX He, X Hu, W Jiang, RL Liu, D Zhang, J Zhang, ZH Li, and YX Luan*. Rational design of a new self-codelivery system from redox-sensitive camptothecin-cytarabine conjugate assembly for effectively synergistic anticancer therapy,Advanced Healthcare Materials2017, 6, 1700829.
